Genome-wide requirements for resistance to functionally distinct DNA-damaging agents.
The mechanistic and therapeutic differences in the cellular response to DNA-damaging compounds are not completely understood, despite intense study. To expand our knowledge of DNA damage, we assayed the effects of 12 closely related DNA-damaging agents on the complete pool of approximately 4,700 bar...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2005-08-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1189734?pdf=render |