Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity

<p>Abstract</p> <p>Background</p> <p>Bortezomib, a specific and selective inhibitor of the 26S proteasome with antitumor activity against a wide range of malignancies, has been approved for the treatment of relapsed or refractory multiple myeloma and other cancers. Rece...

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Bibliographic Details
Main Authors: Rousseau Raphaël, Brejon Stéphanie, Iacono Isabelle, Boyault Sandrine, Combaret Valérie, Puisieux Alain
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/50