HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC

HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC

Abstract The E3 ubiquitin ligase HECTD3 is homologous with the E6 related protein carboxyl terminus, which plays a vital role in biological modification, including immunoreactivity, drug resistance and apoptosis. Current research indicates that HECTD3 promotes the malignant proliferation of multiple...

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Bibliographic Details
Main Authors: Guanghui Zhang, Qingzong Zhu, Xiaomin Yan, Mingxin Ci, Erhu Zhao, Jianbing Hou, Sicheng Wan, Muhan Lü, Hongjuan Cui
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01001-9

Internet

https://doi.org/10.1038/s41420-022-01001-9

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