Antrodin C Isolated from Antrodia Cinnamomea Induced Apoptosis through ROS/AKT/ERK/P38 Signaling Pathway and Epigenetic Histone Acetylation of TNFα in Colorectal Cancer Cells

Antrodin C Isolated from Antrodia Cinnamomea Induced Apoptosis through ROS/AKT/ERK/P38 Signaling Pathway and Epigenetic Histone Acetylation of TNFα in Colorectal Cancer Cells

Background: Antrodin C, a maleimide derivative compound isolated from the ethanol extract of the mycelium of <i>Antrodia cinnamomea</i>, is an endemic fungus of Taiwan and a potential chemoprotective agent. However, the molecular mechanisms underlying the mode of action of antrodin C on...

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Bibliographic Details
Main Authors: Yung-Yu Hsieh, Ko-Chao Lee, Kung-Chuan Cheng, Kam-Fai Lee, Ya-Ling Yang, Hsin-Tung Chu, Ting-Wei Lin, Chin-Chu Chen, Meng-Chiao Hsieh, Cheng-Yi Huang, Hsing-Chun Kuo, Chih-Chuan Teng
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
antrodin C
colorectal cancer
apoptosis
TNFα
H3K9K14ac
Online Access:https://www.mdpi.com/2076-3921/12/3/764

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https://www.mdpi.com/2076-3921/12/3/764

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