Absent in melanoma 2 (AIM2) in rheumatoid arthritis: novel molecular insights and implications

Absent in melanoma 2 (AIM2) in rheumatoid arthritis: novel molecular insights and implications

Abstract Absent in melanoma 2 (AIM2), a member of the Pyrin and HIN domain protein family, is a cytoplasmic receptor that recognizes double-stranded DNA. AIM2 exhibits limited expression under physiological conditions but is widely expressed in many human diseases, including autoimmune diseases, and...

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Bibliographic Details
Main Authors: Jianan Zhao, Shicheng Guo, Steven J. Schrodi, Dongyi He
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
Rheumatoid arthritis
Autoimmune disease
Absent in melanoma 2
Inflammation
Pyroptosis
PANoptosis
Online Access:https://doi.org/10.1186/s11658-022-00402-z

Internet

https://doi.org/10.1186/s11658-022-00402-z

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