Asiatic Acid Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β/HIF-1α Signaling in Rat H9c2 Cardiomyocytes

Asiatic Acid Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β/HIF-1α Signaling in Rat H9c2 Cardiomyocytes

Myocardial ischemic/reperfusion injury results from severe impairment of coronary blood supply and leads to irreversible cell death, with limited therapeutic possibilities. Asiatic acid is a pentacyclic triterpenoid derived from the tropical medicinal plant Centella asiatica and serves a variety of...

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Bibliographic Details
Main Authors: Xiang Huang, Li Zuo, Yanni Lv, Chuqiao Chen, Yaqin Yang, Hongbo Xin, Yunman Li, Yisong Qian
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Molecules
Subjects:
asiatic acid
myocardial ischemia
OGD/R
Akt
HIF-1α
Online Access:http://www.mdpi.com/1420-3049/21/9/1248

Internet

http://www.mdpi.com/1420-3049/21/9/1248

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