Chromosomal integration of Tn5253 occurs downstream of a conserved 11-bp sequence of the rbgA gene in Streptococcus pneumoniae and in all the other known hosts of this integrative conjugative element (ICE)

Chromosomal integration of Tn5253 occurs downstream of a conserved 11-bp sequence of the rbgA gene in Streptococcus pneumoniae and in all the other known hosts of this integrative conjugative element (ICE)

Abstract Background Tn5253, a composite Integrative Conjugative Element (ICE) of Streptococcus pneumoniae carrying tet(M) and cat resistance determinants, was found to (i) integrate at specific 83-bp integration site (attB), (ii) produce circular forms joined by a 84-bp sequence (attTn), and (iii) r...

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Bibliographic Details
Main Authors: Francesco Santoro, Valeria Fox, Alessandra Romeo, Elisa Lazzeri, Gianni Pozzi, Francesco Iannelli
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Mobile DNA
Subjects:
Mobile genetic elements (MGE)
Integrative conjugative element (ICE)
Conjugative transposon
Conjugation
Attachment site
Circular form
Online Access:https://doi.org/10.1186/s13100-021-00253-z

Internet

https://doi.org/10.1186/s13100-021-00253-z

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