Cellular and molecular alterations in neurons and glial cells in inherited retinal degeneration

Cellular and molecular alterations in neurons and glial cells in inherited retinal degeneration

Multiple gene mutations have been associated with inherited retinal dystrophies (IRDs). Despite the spectrum of phenotypes caused by the distinct mutations, IRDs display common physiopathology features. Cell death is accompanied by inflammation and oxidative stress. The vertebrate retina has several...

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Bibliographic Details
Main Authors: Natalia Martínez-Gil, Victoria Maneu, Oksana Kutsyr, Laura Fernández-Sánchez, Xavier Sánchez-Sáez, Carla Sánchez-Castillo, Laura Campello, Pedro Lax, Isabel Pinilla, Nicolás Cuenca
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroanatomy
Subjects:
retinal degeneration
cellular responses
oxidative stress
inflammation
reactive oxygen species
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2022.984052/full

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https://www.frontiersin.org/articles/10.3389/fnana.2022.984052/full

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