A network-guided protocol to discover susceptibility genes in genome-wide association studies using stability selection
Summary: We present a network-based protocol to discover susceptibility genes in case-control genome-wide association studies (GWASs). In short, this protocol looks for biomarkers that are informative of disease status and interconnected in an underlying biological network. This boosts discovery and...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166722008784 |