Understanding Restrictive Versus Liberal Fluid Therapy for Major Abdominal Surgery Trial Results: Did Liberal Fluids Associate With Increased Endothelial Injury Markers?

Objectives:. Liberal fluid strategies in critically ill patients are associated with harm, thought to be due to endothelial and glycocalyx injury. As the restrictive versus liberal fluid therapy for major abdominal surgery trial not only failed to report survival benefit with restrictive fluids but...

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Bibliographic Details
Main Authors: Shailesh Bihari, PhD, Dani-Louise Dixon, PhD, Thomas Painter, FANZCA, Paul Myles, MD, Andrew D. Bersten, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-01-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000316