Neutralizing anti-interleukin-1β antibodies modulate fetal blood–brain barrier function after ischemia

Neutralizing anti-interleukin-1β antibodies modulate fetal blood–brain barrier function after ischemia

We have previously shown that increases in blood–brain barrier permeability represent an important component of ischemia–reperfusion related brain injury in the fetus. Pro-inflammatory cytokines could contribute to these abnormalities in blood–brain barrier function. We have generated pharmacologica...

Full description

Bibliographic Details
Main Authors: Xiaodi Chen, Grazyna B. Sadowska, Jiyong Zhang, Jeong-Eun Kim, Erin E. Cummings, Courtney A. Bodge, Yow-Pin Lim, Oleksandr Makeyev, Walter G. Besio, John Gaitanis, Steven W. Threlkeld, William A. Banks, Barbara S. Stonestreet
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
Blood–brain barrier
Brain
Cytokines
Interleukin-1β
Ischemia–reperfusion
Monoclonal antibody
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002794

Internet

http://www.sciencedirect.com/science/article/pii/S0969996114002794

Similar Items