OccuPeak: ChIP-Seq peak calling based on internal background modelling.

OccuPeak: ChIP-Seq peak calling based on internal background modelling.

ChIP-seq has become a major tool for the genome-wide identification of transcription factor binding or histone modification sites. Most peak-calling algorithms require input control datasets to model the occurrence of background reads to account for local sequencing and GC bias. However, the GC-cont...

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Bibliographic Details
Main Authors: Bouke A de Boer, Karel van Duijvenboden, Malou van den Boogaard, Vincent M Christoffels, Phil Barnett, Jan M Ruijter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4061025?pdf=render

Internet

http://europepmc.org/articles/PMC4061025?pdf=render

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