IL-1β Blockade Attenuates Thrombosis in a Neutrophil Extracellular Trap-Dependent Breast Cancer Model

IL-1β Blockade Attenuates Thrombosis in a Neutrophil Extracellular Trap-Dependent Breast Cancer Model

Cancer patients are at increased risk of developing thrombosis, comorbidity that has been associated with increased neutrophil counts and the formation of neutrophil extracellular traps (NETs). Interleukin-1β (IL-1β) modulates the expression of granulocyte colony-stimulating factor (G-CSF), a cytoki...

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Bibliographic Details
Main Authors: Tainá Gomes, Carolina B. S. Várady, André L. Lourenço, Daniella M. Mizurini, Araci M. R. Rondon, Ana C. Leal, Barbara S. Gonçalves, Dumith Chequer Bou-Habib, Emiliano Medei, Robson Q. Monteiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
cancer
IL-1β
G-CSF
neutrophil extracellular trap (NET)
thrombosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02088/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02088/full

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