Costunolide prevents renal ischemia-reperfusion injury in rats by reducing autophagy, apoptosis, inflammation, and DNA damage

Costunolide prevents renal ischemia-reperfusion injury in rats by reducing autophagy, apoptosis, inflammation, and DNA damage

Objective(s): Renal ischemia-reperfusion (I/R) is a vital health condition leading to acute kidney injury. Costunolide (COST) is an actively used molecule clinically for its anti-inflammatory, antioxidant, and immunomodulatory properties. In the present study, we searched for the possible protective...

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Bibliographic Details
Main Authors: Mustafa Güler, Erol Akpinar, Ayhan Tanyeli, Selim Çomakli, Yasin Bayir
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
apoptosis
autophagy
costunolide
rat
renal ischemia-reperfusion
Online Access:https://ijbms.mums.ac.ir/article_22554_c058e9719e6da96bb59e41e98db2be07.pdf

Internet

https://ijbms.mums.ac.ir/article_22554_c058e9719e6da96bb59e41e98db2be07.pdf

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