DEVELOPMENT OF MURINE STEM CELLS WITH CONDITIONAL KNOCKOUT OF HUMANIZED SNCA GENE

DEVELOPMENT OF MURINE STEM CELLS WITH CONDITIONAL KNOCKOUT OF HUMANIZED SNCA GENE

α-synuclein is one of the key molecular links in the pathogenesis of Parkinson’s disease. The accumulated data indicate that pathogenic mutations in the Snca gene are associated with the development of neurodegenerative brain damage, indicating the relevance of studying the synuclein neurobiological...

Full description

Bibliographic Details
Main Authors: E. A. Patrakhanov, V. M. Pokrovsky, A. Yu. Karagodina, A. M. Krayushkina, N. S. Zhunusov, A. V. Deykin, M. V. Korokin, M. V. Pokrovsky, O. B. Altukhova
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2023-02-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
α-синуклеин
нейродегенерация
болезнь паркинсона
кондиционный нокаут
crispr/cas9
Online Access:https://www.pharmpharm.ru/jour/article/view/1218

Internet

https://www.pharmpharm.ru/jour/article/view/1218

Similar Items