Biomechanical forces enhance directed migration and activation of bone marrow-derived dendritic cells

Abstract Mechanical forces are pervasive in the inflammatory site where dendritic cells (DCs) are activated to migrate into draining lymph nodes. For example, fluid shear stress modulates the movement patterns of DCs, including directness and forward migration indices (FMIs), without chemokine effec...

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Bibliographic Details
Main Authors: Ji-Hun Kang, Hyun Joo Lee, Ok-Hyeon Kim, Yong Ju Yun, Young-Jin Seo, Hyun Jung Lee
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91117-2