The Voltage-Gated Hv1 H<sup>+</sup> Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells

The Voltage-Gated Hv1 H<sup>+</sup> Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells

Myeloid-derived suppressor cells (MDSCs) are key determinants of the immunosuppressive microenvironment in tumors. As ion channels play key roles in the physiology/pathophysiology of immune cells, we aimed at studying the ion channel repertoire in tumor-derived polymorphonuclear (PMN-MDSC) and monoc...

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Bibliographic Details
Main Authors: Marco Cozzolino, Adrienn Gyöngyösi, Eva Korpos, Peter Gogolak, Muhammad Umair Naseem, Judit Kállai, Arpad Lanyi, Gyorgy Panyi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Myeloid-derived suppressor cell
Hv1 proton channel
tumor microenvironment
Online Access:https://www.mdpi.com/1422-0067/24/7/6216

Internet

https://www.mdpi.com/1422-0067/24/7/6216

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