Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2
The dopamine D4 receptor (D4R) is expressed in the retina, prefrontal cortex, and autonomic nervous system and has been implicated in attention deficit hyperactivity disorder (ADHD), substance use disorders, and erectile dysfunction. D4R has also been investigated as a target for antipsychotics due...
| Main Authors: | , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Frontiers Media S.A.
2023-01-01
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| 叢編: | Frontiers in Pharmacology |
| 主題: | |
| 在線閱讀: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1087171/full |