Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy

Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy

Background: In the setting of drug-resistant epilepsy (DRE), the success of surgery depends on the ability to accurately locate the epileptic foci to be resected or disconnected. However, the epileptic foci in a considerable percentage of the DRE patients cannot be adequately localised. This warrant...

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Bibliographic Details
Main Authors: Cong Wang, Jianping Zhang, Shaoli Song, Zhi Li, Shujie Yin, Wenjia Duan, Zixuan Wei, Ming Qi, Wanbing Sun, Lu Zhang, Luo Chen, Xihui Gao, Ying Mao, Hao Wang, Liang Chen, Cong Li
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:EBioMedicine
Subjects:
Low-density lipoprotein receptor-related protein-1 (LRP1)
Epilepsy
Magnetic resonance imaging (MRI)
Single-photon emission computed tomography (SPECT)
Blood-brain barrier (BBB)
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420305326

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