Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin

Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin

In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of nitric oxide (NO) is believed to be partly re...

Full description

Bibliographic Details
Main Authors: Mueller Nicolas J, Walter Roland Β, Linscheid Philippe, Schaffner Andreas, Schoedon Gabriele
Format: Article
Language:English
Published: De Gruyter 2002-11-01
Series:Pteridines
Subjects:
inflammation
vascular endothelial cell,nitric oxide synthase
pteridine
tetrahydrobiopterin;4-amino-tetrahydrobiopterin
5-methyl-tetrahydrobiopterin
Online Access:https://doi.org/10.1515/pteridines.2002.13.4.126

Internet

https://doi.org/10.1515/pteridines.2002.13.4.126

Similar Items