Lineage Replacement Associated with Fitness Gain in Mammalian Cells and <i>Aedes aegypti</i>: A Catalyst for Dengue Virus Type 2 Transmission

Shifting of virus serotypes and clade replacement events are known to drive dengue epidemics. However, only a few studies have attempted to elucidate the virus attributes that contribute to such epidemics. In 2007, Singapore experienced a dengue outbreak affecting more than 8000 individuals. The out...

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Bibliographic Details
Main Authors: Cheong Huat Tan, Hapuarachchige Chanditha Hapuarachchi, Li Kiang Tan, Pei Sze Jeslyn Wong, Mei Zhi Irene Li, Wing Yan Wong, Lee Ching Ng
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/10/6/1100