[99mTc]-labelled anti-Programmed Death-Ligand 1 single-domain antibody SPECT/CT: a novel imaging biomarker for myocardial PD-L1 expression

Abstract Background Myocardial programmed death-ligand 1 (PD-L1) expression is implicated in immune checkpoint inhibitor (ICI)-associated myocarditis. Measurement of myocardial PD-L1 expression may have potential use as a mechanistic and predictive biomarker. The aim of this study was to determine n...

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Bibliographic Details
Main Authors: Muhummad Sohaib Nazir, Daniel Johnathan Hughes, Gitasha Chand, Kathryn Adamson, Jessica Johnson, Damion Bailey, Victoria Gibson, Hong Hoi Ting, Alexander R. Lyon, Gary J. R. Cook, PECan study group
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:EJNMMI Research
Subjects:
Online Access:https://doi.org/10.1186/s13550-023-00990-7