Stage-Specific Non-Coding RNA Expression Patterns during In Vitro Human B Cell Differentiation into Antibody Secreting Plasma Cells

Stage-Specific Non-Coding RNA Expression Patterns during In Vitro Human B Cell Differentiation into Antibody Secreting Plasma Cells

The differentiation of B cells into antibody secreting plasma cells (PCs) is governed by a strict regulatory network that results in expression of specific transcriptomes along the activation continuum. In vitro models yielding significant numbers of PCs phenotypically identical to the in vivo state...

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Bibliographic Details
Main Authors: Renee C. Tschumper, Dominique B. Hoelzinger, Denise K. Walters, Jaime I. Davila, Collin A. Osborne, Diane F. Jelinek
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Non-Coding RNA
Subjects:
non-coding RNA
plasma cells
in vitro B cell differentiation
human B lymphocytes
RNA-seq
Online Access:https://www.mdpi.com/2311-553X/8/1/15

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https://www.mdpi.com/2311-553X/8/1/15

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