HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis

HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis

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IntroductionGenetic predisposition to autoimmune encephalitis with antibodies against N-methyl-D-aspartate receptor (NMDAR) is poorly understood. Given the diversity of associated environmental factors (tumors, infections), we hypothesized that human leukocyte antigen (HLA) and killer-cell immunoglo...

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Main Authors: Vicente Peris Sempere, Guo Luo, Sergio Muñiz-Castrillo, Anne-Laurie Pinto, Géraldine Picard, Véronique Rogemond, Maarten J. Titulaer, Carsten Finke, Frank Leypoldt, Gregor Kuhlenbäumer, GENERATE study group, Hannah F. Jones, Russell C. Dale, Sophie Binks, Sarosh R. Irani, Anna E. Bastiaansen, Juna M. de Vries, Marienke A. A. M. de Bruijn, Dave L. Roelen, Tae-Joon Kim, Kon Chu, Soon-Tae Lee, Takamichi Kanbayashi, Nicholas R. Pollock, Katherine M. Kichula, Abigail Mumme-Monheit, Jérôme Honnorat, Paul J. Norman, Emmanuel Mignot
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Immunology
Subjects:
anti-NMDAR encephalitis
KIR
KIR3DL3
KIR2DL4
HLA
DQA1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423149/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423149/full

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