TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines

TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines

IntroductionT-cell immunoglobulin and mucin domain-3 (TIM-3) is a transmembrane molecule first identified as an immunoregulator. This molecule is also expressed on leukemic cells in acute myeloid leukemia and master cell survival and proliferation. In this study, we aimed to explore the effect of TI...

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Bibliographic Details
Main Authors: Mahnaz Rezaei, Mustafa Ghanadian, Behrooz Ghezelbash, Abolfazl Shokouhi, Alexandr V. Bazhin, Andrey A. Zamyatnin, Mazdak Ganjalikhani-Hakemi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
acute myeloid leukemia
TIM-3
immunometabolism
glucose metabolism
lipid metabolism
galectin-9
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267578/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267578/full

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