Lamin B1 overexpression alters chromatin organization and gene expression

Lamin B1 overexpression alters chromatin organization and gene expression

ABSTRACTPeripheral heterochromatin positioning depends on nuclear envelope associated proteins and repressive histone modifications. Here we show that overexpression (OE) of Lamin B1 (LmnB1) leads to the redistribution of peripheral heterochromatin into heterochromatic foci within the nucleoplasm. T...

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Bibliographic Details
Main Authors: Jeanae M. Kaneshiro, Juliana S. Capitanio, Martin W. Hetzer
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Nucleus
Subjects:
Chromatin organization
gene expression
nuclear lamina
nuclear envelope
heterochromatin
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2023.2202548

Internet

https://www.tandfonline.com/doi/10.1080/19491034.2023.2202548

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