Dedifferentiated human umbilical cord mesenchymal stem cell reprogramming of endogenous hSDF-1α expression participates in neural restoration in hypoxic-ischemic brain damage rats

Dedifferentiated human umbilical cord mesenchymal stem cell reprogramming of endogenous hSDF-1α expression participates in neural restoration in hypoxic-ischemic brain damage rats

The transplantation of human umbilical cord mesenchymal stem cells (hUC-MSCs) can promote hypoxic-ischemic brain damage (HIBD) nerve repair, but finding suitable seed cells to optimize transplantation and improve treatment efficiency is an urgent problem to be solved. In this study, we induced hUC-M...

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Bibliographic Details
Main Authors: Zhou Xiaoqin, Liu Jia, Dai Mengjie, Gu Jialu, Bi Yang, Wang Yuting, Hu Huajian, Liu Bo, Zhang Xiaojun, Li Zhongyue, Chen Jie, Li Tingyu, Zhan Xue
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-05-01
Series:Genes and Diseases
Subjects:
Dedifferentiation
Human umbilical cord mesenchymal stem cells
Hypoxic-ischemic brain damage
Neurorestoration
Reprogramming
Stromal cell-derived factor-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300209

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http://www.sciencedirect.com/science/article/pii/S2352304220300209

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