Computational Biology Helps Understand How Polyploid Giant Cancer Cells Drive Tumor Success

Computational Biology Helps Understand How Polyploid Giant Cancer Cells Drive Tumor Success

Precision and organization govern the cell cycle, ensuring normal proliferation. However, some cells may undergo abnormal cell divisions (neosis) or variations of mitotic cycles (endopolyploidy). Consequently, the formation of polyploid giant cancer cells (PGCCs), critical for tumor survival, resist...

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Bibliographic Details
Main Authors: Matheus Correia Casotti, Débora Dummer Meira, Aléxia Stefani Siqueira Zetum, Bruno Cancian de Araújo, Danielle Ribeiro Campos da Silva, Eldamária de Vargas Wolfgramm dos Santos, Fernanda Mariano Garcia, Flávia de Paula, Gabriel Mendonça Santana, Luana Santos Louro, Lyvia Neves Rebello Alves, Raquel Furlani Rocon Braga, Raquel Silva dos Reis Trabach, Sara Santos Bernardes, Thomas Erik Santos Louro, Eduardo Cremonese Filippi Chiela, Guido Lenz, Elizeu Fagundes de Carvalho, Iúri Drumond Louro
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Genes
Subjects:
polyploid giant cancer cells (PGCCs)
bioinformatics
systems biology
tumor evolution
Online Access:https://www.mdpi.com/2073-4425/14/4/801

Internet

https://www.mdpi.com/2073-4425/14/4/801

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