Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks

Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks

Summary: Replication of a damaged DNA template can threaten the integrity of the genome, requiring the use of various mechanisms to tolerate DNA lesions. The Smc5/6 complex, together with the Nse2/Mms21 SUMO ligase, plays essential roles in genome stability through undefined tasks at damaged replica...

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Bibliographic Details
Main Authors: Mariel Zapatka, Irene Pociño-Merino, Hayat Heluani-Gahete, Marcelino Bermúdez-López, Marc Tarrés, Eva Ibars, Roger Solé-Soler, Pilar Gutiérrez-Escribano, Sonia Apostolova, Celia Casas, Luis Aragon, Ralf Wellinger, Neus Colomina, Jordi Torres-Rosell
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314561

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http://www.sciencedirect.com/science/article/pii/S2211124719314561

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