Rice Nudix Hydrolase OsNUDX2 Sanitizes Oxidized Nucleotides

Nudix hydrolase (NUDX) hydrolyzes 8-oxo-(d)GTP to reduce the levels of oxidized nucleotides in the cells. 8-oxo-(d)GTP produced by reactive oxygen species (ROS) is incorporated into DNA/RNA and mispaired with adenine, causing replicational and transcriptional errors. Here, we identified a rice <i...

ver descrição completa

Detalhes bibliográficos
Principais autores: Yuki Kondo, Kazuhide Rikiishi, Manabu Sugimoto
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2022-09-01
coleção:Antioxidants
Assuntos:
Acesso em linha:https://www.mdpi.com/2076-3921/11/9/1805