Rice Nudix Hydrolase OsNUDX2 Sanitizes Oxidized Nucleotides
Nudix hydrolase (NUDX) hydrolyzes 8-oxo-(d)GTP to reduce the levels of oxidized nucleotides in the cells. 8-oxo-(d)GTP produced by reactive oxygen species (ROS) is incorporated into DNA/RNA and mispaired with adenine, causing replicational and transcriptional errors. Here, we identified a rice <i...
Principais autores: | , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
MDPI AG
2022-09-01
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coleção: | Antioxidants |
Assuntos: | |
Acesso em linha: | https://www.mdpi.com/2076-3921/11/9/1805 |