Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disorder. It is caused by loss-of-function mutations in the dystrophin gene. Currently, there is no cure. A highly promising therapeutic strategy is to replace or repair the defective dystrophin gene by gene therapy. Numerous animal m...

Full description

Bibliographic Details
Main Authors: Joe W. McGreevy, Chady H. Hakim, Mark A. McIntosh, Dongsheng Duan
Format: Article
Language:English
Published: The Company of Biologists 2015-03-01
Series:Disease Models & Mechanisms
Subjects:
Duchenne muscular dystrophy
Dystrophin
Animal model
Canine DMD
Gene therapy
Online Access:http://dmm.biologists.org/content/8/3/195

Internet

http://dmm.biologists.org/content/8/3/195

Similar Items