Is Resistance to Dolutegravir Possible When This Drug Is Used in First-Line Therapy?

Dolutegravir (DTG) is an HIV integrase inhibitor that was recently approved for therapy by the Food and Drug Administration in the United States. When used as part of first-line therapy, DTG is the only HIV drug that has not selected for resistance mutations in the clinic. We believe that this is du...

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Bibliographic Details
Main Authors: Thibault Mesplède, Mark A. Wainberg
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/6/9/3377