The Antiviral RNAi Response in Vector and Non-vector Cells against Orthobunyaviruses.

BACKGROUND:Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and Piwi-interacting RNA (piRNA) pathways, but direct...

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Bibliographic Details
Main Authors: Isabelle Dietrich, Xiaohong Shi, Melanie McFarlane, Mick Watson, Anne-Lie Blomström, Jessica K Skelton, Alain Kohl, Richard M Elliott, Esther Schnettler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5245901?pdf=render