Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
The mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to...
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Format: | Article |
Language: | English |
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Nature Portfolio
2019-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-11402-7 |