Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
The mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2019-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-11402-7 |
| _version_ | 1818835209449111552 |
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| author | R. Dean Astumian |
| author_facet | R. Dean Astumian |
| author_sort | R. Dean Astumian |
| collection | DOAJ |
| description | The mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to drive non-equilibrium response by an information ratchet mechanism. |
| first_indexed | 2024-12-19T02:47:05Z |
| format | Article |
| id | doaj.art-e4c02fcd69d14091b57450d7646e9e60 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T02:47:05Z |
| publishDate | 2019-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e4c02fcd69d14091b57450d7646e9e602022-12-21T20:38:49ZengNature PortfolioNature Communications2041-17232019-08-0110111410.1038/s41467-019-11402-7Kinetic asymmetry allows macromolecular catalysts to drive an information ratchetR. Dean Astumian0Department of Physics, University of MaineThe mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to drive non-equilibrium response by an information ratchet mechanism.https://doi.org/10.1038/s41467-019-11402-7 |
| spellingShingle | R. Dean Astumian Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet Nature Communications |
| title | Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet |
| title_full | Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet |
| title_fullStr | Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet |
| title_full_unstemmed | Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet |
| title_short | Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet |
| title_sort | kinetic asymmetry allows macromolecular catalysts to drive an information ratchet |
| url | https://doi.org/10.1038/s41467-019-11402-7 |
| work_keys_str_mv | AT rdeanastumian kineticasymmetryallowsmacromolecularcatalyststodriveaninformationratchet |