MicroRNA-375 Is Induced during Astrocyte-to-Neuron Reprogramming and Promotes Survival of Reprogrammed Neurons when Overexpressed

MicroRNA-375 Is Induced during Astrocyte-to-Neuron Reprogramming and Promotes Survival of Reprogrammed Neurons when Overexpressed

While astrocyte-to-neuron (AtN) reprogramming holds great promise in regenerative medicine, the molecular mechanisms that govern this unique biological process remain elusive. To understand the function of miRNAs during the AtN reprogramming process, we performed RNA-seq of both mRNAs and miRNAs on...

Full description

Bibliographic Details
Main Authors: Xuanyu Chen, Ivan Sokirniy, Xin Wang, Mei Jiang, Natalie Mseis-Jackson, Christine Williams, Kristopher Mayes, Na Jiang, Brendan Puls, Quansheng Du, Yang Shi, Hedong Li
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
astrocyte
microRNA
miR-375
miR-124
NeuroD1
neuronal reprogramming
Online Access:https://www.mdpi.com/2073-4409/12/17/2202

Internet

https://www.mdpi.com/2073-4409/12/17/2202

Similar Items