Retrochalcone Echinatin Triggers Apoptosis of Esophageal Squamous Cell Carcinoma via ROS- and ER Stress-Mediated Signaling Pathways

Retrochalcone Echinatin Triggers Apoptosis of Esophageal Squamous Cell Carcinoma via ROS- and ER Stress-Mediated Signaling Pathways

Esophageal squamous cell carcinoma (ESCC) is a poor prognostic cancer with a low five-year survival rate. Echinatin (Ech) is a retrochalone from licorice. It has been used as a herbal medicine due to its anti-inflammatory and anti-oxidative effects. However, its anticancer activity or underlying mec...

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Bibliographic Details
Main Authors: Ah-Won Kwak, Joon-Seok Choi, Mee-Hyun Lee, Ha-Na Oh, Seung-Sik Cho, Goo Yoon, Kangdong Liu, Jung-Il Chae, Jung-Hyun Shim
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
esophageal squamous cell carcinoma
echinatin
reactive oxygen species
c-jun n-terminal kinase
p38
Online Access:https://www.mdpi.com/1420-3049/24/22/4055

Internet

https://www.mdpi.com/1420-3049/24/22/4055

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