Mathematical modelling of the dynamics of image-informed tumor habitats in a murine model of glioma

Abstract Tumors exhibit high molecular, phenotypic, and physiological heterogeneity. In this effort, we employ quantitative magnetic resonance imaging (MRI) data to capture this heterogeneity through imaging-based subregions or “habitats” in a murine model of glioma. We then demonstrate the ability...

Full description

Bibliographic Details
Main Authors: Kalina P. Slavkova, Sahil H. Patel, Zachary Cacini, Anum S. Kazerouni, Andrea L. Gardner, Thomas E. Yankeelov, David A. Hormuth
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30010-6