Mass cytometry and single-cell RNA sequencing reveal immune cell characteristics of active and inactive phases of Crohn’s disease

Mass cytometry and single-cell RNA sequencing reveal immune cell characteristics of active and inactive phases of Crohn’s disease

ObjectivesFor Crohn’s disease (CD), the alternation of the active phase and inactive phase may be related to humoral immunity and cellular immunity. This study aims to understand the characteristics of immune cells in patients with active CD (CDa) and inactive CD (CDin).MethodsMass cytometry (CyTOF)...

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Bibliographic Details
Main Authors: Wenjia Lin, Shiying Liu, Zhuojian Huang, Haiwen Li, Tianyu Lu, Yongxin Luo, Jiamin Zhong, Zewen Xu, Yu Liu, Yanwu Li, Peiwu Li, Qian Xu, Jiazhong Cai, Huibiao Li, Xin-lin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Medicine
Subjects:
Crohn’s disease
CyTOF
scRNA-seq
immune cell
monocyte
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1064106/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.1064106/full

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