Single particle cryo-EM structure of the outer hair cell motor protein prestin

Prestin, expressed in outer hair cell (OHC), belongs to the Slc26 transporter family and functions as a voltage-driven motor that drives OHC electromotility. Here, the authors report cryo-EM structure and characterization of gerbil prestin, with insights into its mechanism of action.

Bibliographic Details
Main Authors: Carmen Butan, Qiang Song, Jun-Ping Bai, Winston J. T. Tan, Dhasakumar Navaratnam, Joseph Santos-Sacchi
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27915-z