Design and Evaluation of Autophagy-Inducing Particles for the Treatment of Abnormal Lipid Accumulation

Design and Evaluation of Autophagy-Inducing Particles for the Treatment of Abnormal Lipid Accumulation

Autophagy is a fundamental housekeeping process by which cells degrade their components to maintain homeostasis. Defects in autophagy have been associated with aging, neurodegeneration and metabolic diseases. Non-alcoholic fatty liver diseases (NAFLDs) are characterized by hepatic fat accumulation w...

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Bibliographic Details
Main Authors: Stavroula Zagkou, Valentine Marais, Narimane Zeghoudi, Edouard Le Guillou, Eeva-Liisa Eskelinen, Ganna Panasyuk, Bernard Verrier, Charlotte Primard
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
autophagy
polylactic acid
polymeric nanoparticles
liver targeting
Tat-Beclin peptide
non-alcoholic fatty liver disease
Online Access:https://www.mdpi.com/1999-4923/14/7/1379

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https://www.mdpi.com/1999-4923/14/7/1379

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