NS3 genomic sequencing and phylogenetic analysis as alternative to a commercially available assay to reliably determine hepatitis C virus subtypes 1a and 1b.

To evaluate the use of hepatitis C virus (HCV) NS3 sequencing as alternative to the comercially available Versant HCV 2.0 reverse hybridization line-probe assay (LiPA 2.0) to determine HCV genotype 1 (HCV-1) subtypes.A cohort of 104 patients infected by HCV-1 according to LiPA 2.0 was analyzed in a...

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Bibliographic Details
Main Authors: Karin Neukam, Alfredo P Martínez, Andrés C A Culasso, Ezequiel Ridruejo, Gabriel García, Federico A Di Lello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5533332?pdf=render