Return of non-ACMG recommended incidental genetic findings to pediatric patients: considerations and opportunities from experiences in genomic sequencing

Return of non-ACMG recommended incidental genetic findings to pediatric patients: considerations and opportunities from experiences in genomic sequencing

Abstract Background The uptake of exome/genome sequencing has introduced unexpected testing results (incidental findings) that have become a major challenge for both testing laboratories and providers. While the American College of Medical Genetics and Genomics has outlined guidelines for laboratory...

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Bibliographic Details
Main Authors: Kevin M. Bowling, Michelle L. Thompson, Melissa A. Kelly, Sarah Scollon, Anne M. Slavotinek, Bradford C. Powell, Brian M. Kirmse, Laura G. Hendon, Kyle B. Brothers, Bruce R. Korf, Gregory M. Cooper, John M. Greally, Anna C. E. Hurst
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Genome Medicine
Subjects:
Incidental findings
Genomics
Genetic testing
Pediatrics
Disease severity
Personal utility
Online Access:https://doi.org/10.1186/s13073-022-01139-2

Internet

https://doi.org/10.1186/s13073-022-01139-2

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