MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of <i>HIF-1α</i> and <i>ANGPT2</i>

MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of <i>HIF-1α</i> and <i>ANGPT2</i>

A high-fat diet is responsible for hepatic fat accumulation that sustains chronic liver damage and increases the risks of steatosis and hepatocellular carcinoma (HCC). MicroRNA-29a (miR-29a), a key regulator of cellular behaviors, is present in anti-fibrosis and modulator tumorigenesis. However, the...

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Bibliographic Details
Main Authors: Ying-Hsien Huang, Wei-Shiung Lian, Feng-Sheng Wang, Pei-Wen Wang, Hung-Yu Lin, Ming-Chao Tsai, Ya-Ling Yang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
miR-29a
hepatocellular carcinoma
HIF-1α
ANGPT2
Online Access:https://www.mdpi.com/1422-0067/23/3/1636

Internet

https://www.mdpi.com/1422-0067/23/3/1636

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