Association of Plasma Claudin-5 with Age and Alzheimer Disease

Association of Plasma Claudin-5 with Age and Alzheimer Disease

The blood–brain barrier (BBB) plays pivotal roles in synaptic and neuronal functioning by sealing the space between adjacent microvascular endothelial cells. BBB breakdown is present in patients with mild cognitive impairment (MCI) or Alzheimer disease (AD). Claudin-5 (CLDN-5) is a tetra-spanning pr...

Full description

Bibliographic Details
Main Authors: Keisuke Tachibana, Ryuichi Hirayama, Naoyuki Sato, Kotaro Hattori, Takashi Kato, Hiroyuki Takeda, Masuo Kondoh
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
blood–brain barrier
claudin-5
tight junction
biomarker
dementia
Alzheimer disease
Online Access:https://www.mdpi.com/1422-0067/25/3/1419

Internet

https://www.mdpi.com/1422-0067/25/3/1419

Similar Items