New insights into MAIT cells in autoimmune diseases

New insights into MAIT cells in autoimmune diseases

Mucosal-associated invariant T (MAIT) cells are resident T cells that express semi-invariant TCR chains and are restricted by monomorphic major histocompatibility complex (MHC) class I-related molecules (MR1). MAIT cells can be activated by microbial-specific metabolites (MR1-dependent mode) or cyto...

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Bibliographic Details
Main Authors: Qi Fan, He Nan, Zhe Li, Bingtong Li, Fangze Zhang, Liqi Bi
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Mucosal-associated invariant T cell
Dual functions
Activation mechanisms
Autoimmune diseases
Proinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223000380

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http://www.sciencedirect.com/science/article/pii/S0753332223000380

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