B7H3 targeting gold nanocage pH-sensitive conjugates for precise and synergistic chemo-photothermal therapy against NSCLC

Abstract Background The combination of drug delivery with immune checkpoint targeting has been extensively studied in cancer therapy. However, the clinical benefit for patients from this strategy is still limited. B7 homolog 3 protein (B7-H3), also known as CD276 (B7-H3/CD276), is a promising therap...

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Bibliographic Details
Main Authors: Bing Chen, Kaifan Zheng, Shubin Fang, Kangping Huang, Chengchao Chu, Junyang Zhuang, Jin Lin, Shaoguang Li, Hong Yao, Ailin Liu, Gang Liu, Jizhen Lin, Xinhua Lin
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-023-02078-9