Evidence for interaction of the NLRP3 inflammasome and Bruton’s tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta
An inflammatory microenvironment has been shown to play an important role in the growth and metastasis of tumors. The NLRP3 inflammasome is a multi-protein complex of the innate immune system that is responsible for the production of the potent inflammatory cytokine IL-1β. Tumor- associated macropha...
| Hauptverfasser: | , , , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Taylor & Francis Group
2019-11-01
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| Schriftenreihe: | OncoImmunology |
| Schlagworte: | |
| Online Zugang: | http://dx.doi.org/10.1080/2162402X.2019.1659704 |