Tim-3 signaling blockade with α-lactose induces compensatory TIGIT expression in Plasmodium berghei ANKA-infected mice

Tim-3 signaling blockade with α-lactose induces compensatory TIGIT expression in Plasmodium berghei ANKA-infected mice

Abstract Background Malaria, one of the largest health burdens worldwide, is caused by Plasmodium spp. infection. Upon infection, the host’s immune system begins to clear the parasites. However, Plasmodium species have evolved to escape the host’s immune clearance. T-cell immunoglobulin and mucin do...

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Bibliographic Details
Main Authors: Yiwei Zhang, Ning Jiang, Ting Zhang, Ran Chen, Ying Feng, Xiaoyu Sang, Na Yang, Qijun Chen
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Parasites & Vectors
Subjects:
Plasmodium berghei
Tim-3
Immune escape
Cytokine
α-lactose
TIGIT
Online Access:http://link.springer.com/article/10.1186/s13071-019-3788-x

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http://link.springer.com/article/10.1186/s13071-019-3788-x

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