The association of HLA-G polymorphisms and the synergistic effect of sMICA and sHLA-G with chronic kidney disease and allograft acceptance.

The association of HLA-G polymorphisms and the synergistic effect of sMICA and sHLA-G with chronic kidney disease and allograft acceptance.

The HLA-G and MICA genes are stimulated under inflammatory conditions and code for soluble (sMICA and sHLA-G) or membrane-bound molecules that exhibit immunomodulatory properties. It is still unclear whether they would have a synergistic or antagonistic effect on the immunomodulation of the inflamma...

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Bibliographic Details
Main Authors: Vanessa Hauer, Matilde Risti, Bruna L M Miranda, José S da Silva, Ana L Cidral, Carolina M Pozzi, Fabiana L de C Contieri, Ibrahim A Sadissou, Eduardo A Donadi, Danillo G Augusto, Maria da G Bicalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212750

Internet

https://doi.org/10.1371/journal.pone.0212750

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